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Showing 1 - 10 of 133 results

Status:
US Approved Rx (2015)
First approved in 2015

Class (Stereo):
CHEMICAL (ABSOLUTE)



Uridine triacetate (formally PN401) is an acetylated prodrug of uridine. Following oral administration, uridine triacetate is deacetylated by nonspecific esterases present throughout the body, yielding uridine in the circulation. Uridine triacetate u...
Status:
US Approved Rx (2019)
First approved in 2007

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Sapropterin dihydrochloride, the active pharmaceutical ingredient in Kuvan Tablets, is a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4). Kuvan is indicated to reduce blood phenylalanine (Phe) levels...
Status:
US Approved Rx (2017)
First approved in 2004

Class (Stereo):
CHEMICAL (ABSOLUTE)



Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important ener...
Status:
US Approved Rx (2002)
First approved in 2002

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Sodium oxybate is the sodium salt of gamma-hydroxybutyrate (GHB), an endogenous metabolite of gamma-aminobutyric acid (GABA) a major inhibitory neurotransmitter. Evidence suggests a role for GHB as a neuromodulator/neurotransmitter. Under endogenous ...
Status:
US Approved Rx (1998)
First approved in 1981

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ecraprost [AS 013, Circulase] is a prodrug of prostaglandin E(1) within lipid microspheres that is being developed in Japan by Mitsubishi Pharma Corporation and Asahi Glass. It was originally in development with Welfide Corporation. On 1 October 2001...
Status:
US Approved Rx (1992)
First approved in 1977

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). Dinoprostone is equivalent to prostaglandin E2 (PGE2). It stimulates labor and delivery by stimulating the uterine, and thus terminates pregnancy. Dinoprostone is also capable of stimulat...
Status:
US Approved Rx (2018)
First approved in 1974

Class (Stereo):
CHEMICAL (ACHIRAL)



Dopamine, a sympathomimetic amine vasopressor, is the naturally occurring immediate precursor of norepinephrine. G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the physiological functions of the catecholaminergic neurotr...
Status:
US Approved Rx (1973)
First approved in 1957

Class (Stereo):
CHEMICAL (ABSOLUTE)



L-arginine is a nonessential amino acid that may play an important role in the treatment of cardiovascular disease due to its antiatherogenic, anti-ischemic, antiplatelet, and antithrombotic properties. It has been promoted as a growth stimulant and ...
Status:
US Approved Rx (1998)
First approved in 1951

Class (Stereo):
CHEMICAL (ABSOLUTE)



Hydrocortisone is the main glucocorticoid secreted by the adrenal cortex. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, ...
Status:
US Approved Rx (2013)
First approved in 1947

Class (Stereo):
CHEMICAL (ACHIRAL)



Pyridoxine is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in thos...