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Showing 1 - 6 of 6 results

Status:
US Approved Rx (2013)
First approved in 1959

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

CAPOZIDE (captopril and hydrochlorothiazide tablets, USP) for oral administration combines two antihypertensive agents: captopril and hydrochlorothiazide. The mechanism of action of captopril has not yet been fully elucidated. Captopril prevents the ...
Status:
US Approved Rx (2011)
First approved in 1958

Class (Stereo):
CHEMICAL (ACHIRAL)



Like other thiazides, chlorothiazide promotes water loss from the body (diuretics). It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazid...
Status:
US Previously Marketed
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)



Polythiazide is a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. Polythiazide under brand name Rense is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and cortic...
Status:
US Previously Marketed
First approved in 1960

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Methyclothiazide, a diuretic-antihypertensive agent, is a member of the benzothiadiazine (thiazide) class of drugs. Methyclothiazide has a per mg natriuretic activity approximately 100 times that of the prototype thiazide, chlorothiazide. At maximal ...
Status:
US Previously Marketed
First approved in 1959

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Bendroflumethiazide (INN), formerly bendrofluazide (BAN) is a thiazide diuretic used to treat hypertension. CORZIDE (Nadolol and Bendroflumethiazide Tablets) for oral administration combines two antihypertensive agents: CORGARD (nadolol), a nonselect...
Status:
US Previously Marketed
First approved in 1959

Class (Stereo):
CHEMICAL (ACHIRAL)



Hydroflumethiazide is a thiazide diuretic that inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tubule, which is responsible for 5% of total sodium reabsorption. Normally, the s...