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Showing 1 - 6 of 6 results

Status:
US Approved Rx (2020)
First approved in 1977

Class (Stereo):
CHEMICAL (ACHIRAL)



Cyclobenzaprine is a centrally-acting muscle relaxant which boosts levels of norepinephrine and binds to serotonin receptors in the brain to reduce spasm. Cytochromes P-450 3A4, 1A2, and, to a lesser extent, 2D6, mediate N-demethylation, one of the o...
Status:
US Approved Rx (2015)
First approved in 1962

Class (Stereo):
CHEMICAL (RACEMIC)



Metaxalone (marketed by King Pharmaceuticals under the brand name Skelaxin) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. The mechanism of action of metaxalone in humans ...
Status:
US Approved Rx (1989)
First approved in 1959

Class (Stereo):
CHEMICAL (RACEMIC)



A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. Carisoprodol is indicated for the relief of discomfort associated with acute, painful musculoskeletal condi...
Status:
US Approved Rx (2010)
First approved in 1958

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Chlorzoxazone is a centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisyna...
Status:
US Approved Rx (2003)
First approved in 1957

Class (Stereo):
CHEMICAL (RACEMIC)



Orphenadrine is an anticholinergic drug of the ethanolamine antihistamine class used to treat muscle pain and to help with motor control in Parkinson's disease but has largely been superseded by newer drugs. Orphenadrine binds and inhibits both hista...
Status:
US Approved Rx (2016)
First approved in 1957

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. It is structurally related to guaifenesin. Methocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perha...