Search results for "EU ORPHAN DRUG|Withdrawn|Treatment of multiple myeloma" in comments (approximate match)
Showing 1 - 4 of 4 results
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL). Vorinostat inhibits the enzymatic activity of histone deacetylases HDAC1, HDAC2 and HDAC3 (Cla...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Thalidomide is an immunomodulatory agent with a spectrum of activity that is not fully characterized. Thalidomide is racemic — it contains both left and right-handed isomers in equal amounts: one enantiomer is effective against morning sickness, and ...
Class (Stereo):
CHEMICAL (ACHIRAL)
Perifosine is an orally active alkyl-phosphocholine compound with potential antineoplastic activity. Perifosine is an Akt inhibitor, which targets the pleckstrin homology domain of Akt, thereby preventing its translocation to the plasma membrane. Per...
