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Showing 1 - 3 of 3 results

Status:
US Approved Rx (2025)
First approved in 1988

Class (Stereo):
CHEMICAL (RACEMIC)



Nimodipine is a dihydropyridine calcium antagonist which has been shown to dilate cerebral arterioles and increase cerebral blood flow in animals and humans. It has potential in the treatment of a range of cerebrovascular disorders. Major interest to...
Status:
US Approved Rx (2012)
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Nitrite Ion is a symmetric anion with equal N–O bond lengths. Nitrite is important in biochemistry as a source of the potent vasodilator nitric oxide. Nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation has been class...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Clazosentan is an endothelin receptor antagonist, developed by the Swiss pharmaceutical company Actelion, and licensed to its spin-off, Idorsia. The drug was designed to inhibit endothelin-mediated cerebral vasospasm and associated delayed ischaemic ...