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Showing 1 - 4 of 4 results

Status:
US Approved Rx (2022)
First approved in 2012

Class (Stereo):
CHEMICAL (ACHIRAL)



Cabozantinib (development code name XL184; marketed under the trade name Cometriq) is an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds to and inhibits ...
Status:
US Approved Rx (2011)
First approved in 2011

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Vandetanib, 4-anilinoquinazoline, is an anti-cancer drug that with the potential for use in a broad range of tumour types. In 2011 vandetanib (trade name Caprelsa) was approved by the FDA to treat nonresectable, locally advanced, or metastatic medull...
Status:
US Approved Rx (1998)
First approved in 1998

Class:
PROTEIN

Status:
US Approved Rx (2022)
First approved in 2015

Class (Stereo):
CHEMICAL (ACHIRAL)



Lenvatinib, developed by Eisai Co., is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits othe...