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Status:
US Approved Rx (2019)
First approved in 1970

Class (Stereo):
CHEMICAL (ABSOLUTE)

Esketamine is an S(+)-enantiomer of ketamine. It is a nonselective, noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptor. A nasal spray, containing esketamine, was approved in 2019 for the treatment of treatment-resistant depression in a...