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Showing 1 - 10 of 51 results

Status:
US Approved Rx (2020)
First approved in 2014

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Efinaconazole is triazole used as a 10% topical solution for the treatment of onychomycosis, a fungal infection of the nails. It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC...
Status:
US Approved Rx (2020)
First approved in 2014

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Tavaborole is a boron-based pharmaceutical agent indicated for the topical treatment of toenail onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole acts by inhibit...
Status:
US Approved Rx (2013)
First approved in 2013

Class (Stereo):
CHEMICAL (ABSOLUTE)



Luliconazole (trade names Luzu, Lulicon) is an imidazole antifungal drug. As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum and...
Status:
US Approved Rx (2003)
First approved in 2003

Class (Stereo):
CHEMICAL (RACEMIC)



Sertaconazole is a azole antifungal that is FDA approved for the treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by: Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. S...
Status:
US Approved Rx (1996)
First approved in 1993

Class (Stereo):
CHEMICAL (ACHIRAL)



Butenafine is a synthetic antifungal agent that is structurally and pharmacologically related to allylamine antifungals. The exact mechanism of action has not been established, but it is suggested that butenafine's antifungal activity is exerted thro...
Status:
US Approved Rx (2007)
First approved in 1992

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Terbinafine (brand name Lamisil, Terbisil, Terboderm and others) is an antifungal medication used to treat ringworm and fungal nail infections. Terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the...
Status:
US Approved Rx (2009)
First approved in 1990

Class (Stereo):
CHEMICAL (ACHIRAL)



Fluconazole, a synthetic antifungal agent of the imidazole class, is used to treat vaginal candidiasis. It inhibits the fungal lanosterol 14 alpha-demethylase which thereby prevents the formation of ergosterol which is an essential component in the f...
Status:
US Approved Rx (1992)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Oxiconazole nitrate is 2',4'-dichloro-2-imidazol-1-ylacetophenone (Z)-[0-(2,4-dichlorobenzyl)oxime], mononitrate is an imidazole derivative characterized by a broad fungistatic spectrum. In vitro oxiconazole is highly effective against many dermato...
Status:
US Approved Rx (2019)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a br...
Status:
US Approved Rx (1985)
First approved in 1985

Class (Stereo):
CHEMICAL (RACEMIC)



Sulconazole (trade name Exelderm) is an antifungal medication of the imidazole class. Sulconazole has a broad spectrum of antifungal activity in vitro and has been shown to be an effective topical antifungal agent for the management of superficial fu...