Search results for "Pharmacologic Substance[C1909]|Hormone Therapy Agent[C147908]|Hormone Antagonist[C547]" in comments (approximate match)
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Mozavaptan hydrochloride was approved by Pharmaceuticals and Medical Devices Agency of Japan (PMDA) on July 26, 2006. It was developed and marketed as Physuline® by Otsuka in Japan. Mozavaptan hydrochloride is a vasopressin receptor antagonist. It is...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group. Like spironolactone, it is a prodrug, which is metaboliz...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Aminothiazole is a heterocyclic amine, commonly used as a starting point for synthesis of many compounds. In 1940s aminothiazole was used for the treatment of thyrotoxicosis. It has a direct action on the thyroid and acts by inhibiting T4 synthesis a...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Epristeride is a steroid 5-alpha-reductase inhibitor developed for the treatment of prostatic hyperplasia and acne. The drug reached phase III clinical trial for hyperplasia in the UK, the US and Japan, however, the current status of the drug is unkn...
Cioteronel [CPC 10997, Cyoctol®, X-Andron] is an antiandrogen agent which was in phase II trials for androgenetic alopecia (male pattern baldness), and acne. It was also under development for the oral treatment of benign prostatic hyperplasia, but it...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Zanoterone (or Win 49596), a steroidal androgen receptor antagonist was studied for the treatment of benign prostatic hyperplasia. The drug did not demonstrate a favorable risk-to-benefit profile and further development was stopped.
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Carbimazole is a prodrug for methimazole used to treat hyperthyroidism and thyrotoxicosis during pregnancy and breast breastfeeding. Carbimazole is rapidly metabolized to methimazole, which is responsible for the antithyroid activity. Carbimazole is ...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Methylthiouracil is an orally active thyroid enzyme activity inhibitor. Methylthiouracil was introduced in the mid-1940s for the treatment of hyperthyroidism. Methylthiouracil is no longer in clinical use in most countries, although it may be used to...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Cyproterone acetate is a steroid drug which was developed by Schering A.G (now Bayer). Cyproterone acetate was approved in Canada, Asia, Latin America and Europe for the treatment of sever acne under the name Diane-35 (ethinyl estradiol) and its mech...
