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Search results for "Pharmacologic Substance[C1909]|Antineoplastic Agent[C274]|Antimetabolite" in comments (approximate match)
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Etoprine, a diaminopyrimidine, is a lipid-soluble inhibitor of dihydrofolate reductase. Etoprine inhibits incorporation of deoxyuridine into the DNA. In male rodents, it affected spermatogenesis and induces infertility. Etoprine is considered to exert antineoplastic activity.