U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 731 - 740 of 1990 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Corydine is a naturally occurring compound which can be extracted from plants such as Chelidonium majus, Corydalis marschalliana, C. bulbosa, C slivenensis, Glaucium grandiflorum. Corydine has shown some efficacy as an anti-cancer compound in several cell models and was examined along with related compounds from Stephania dinklagei for antiprotozoal activities. (+)- and (-)- Corydine were tested as neuromuscular blocking agents were it was found that there was a modest preference for (+)-corydine.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


O-Methyl-Gambogic acid Methyl Ester (aka dimethyl-Gambogic acid) is a derivative of gambogic acid a naturally occurring compound found in the resin excreted by the garcinia hanburryi tree in Southeastern Asia. Dimethyl-Gambogic acid demonstrates antiapoptotic activity in T17 cells with an EC50 of 120 nM. It has also shown efficacy against the parasite Trypanosoma brucei with an IC50 of 1.3 micro-M.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)