U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 661 - 670 of 33412 results

Status:
Investigational
Source:
INN:ledaborbactam [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:subasumstat [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:emzadirib [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT04489511: Phase 2 Interventional Completed Stargardt Disease-1
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:caficrestat [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Aldose reductase-IN-1 is an inhibitor of aldose reductase
Status:
Investigational
Source:
INN:coblopasvir [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT00876421: Phase 2 Interventional Completed Overactive Bladder
(2009)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:tigulixostat [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:resiniferatoxin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Resiniferatoxin (RTX or RTX-107) is a vanilloid derived from a cactus-like plant (Euphoria resiniferous) and has anti-inflammatory activity. This compound is an agonist of the transient receptor potential vanilloid 1 (TRPV1). Resiniferatoxin produces analgesia by desensitizing the TRPV1 receptor. Findings of several studies have suggested a potential therapeutic use of the anti-inflammatory effect of resiniferatoxin. Phase I and II clinical trials have been completed or are underway, evaluating the safety and efficacy of resiniferatoxin in pain-related disorders such as osteoarthritis and cancers.
Status:
Investigational
Source:
INN:udonitrectag [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)