U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 49091 - 49100 of 55039 results

Status:
Investigational
Source:
NCT03756103: Phase 2 Interventional Completed Hypertension,Essential
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT00311090: Phase 3 Interventional Completed Deep Venous Thrombosis
(2006)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Idraparinux, a synthetic pentasaccharide is an antithrombin-dependent inhibitor of activated factor X. It was developed for the treatment and prevention of thromboembolic events. However, clinical trials have revealed that idraparinux had lead to bleeding. As a result, Sanofi stopped the development of the drug.
Status:
Investigational
Source:
INN:laudexium metilsulfate
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

LAUDEXIUM is a non-depolarizing neuromuscular blocking agent. It was used in surgical anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Status:
Investigational
Source:
INN:xeruborbactam [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:isuzinaxib [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:lixumistat [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:levophenacylmorphan
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Levophenacylmorphan is the synthetic narcotic analgesic and sedative agent. Levophenacylmorphan have been used as pre-anaesthetic medication. Phenazocine and levophenacylmorphan have similar pharmacologic properties and similar analgesic potency. Levophenacylmorphan is under international control according to the UN Single Convention 1961 and its amendments. It is not found in any pharmaceutical preparations sold in the United States.
Status:
Investigational
Source:
NCT02266745: Phase 2 Interventional Active, not recruiting Advanced Solid Tumors
(2014)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:carafiban
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Carafiban is orally active heterocyclic peptide mimetics fibrinogen IIb/IIIa receptor antagonist with antithrombotic activity. Carafiban is a prodrug, that underwent metabolic transformation to active metabolite des-ethyl- Carafiban, that inhibited dose-dependently and reversibly human platelet aggregation. In conscious dogs, Carafiban showed a high plasma availability of the active moiety of 42±8% and a plasma half-life of 9.9 h after oral administration as measured by bioassay. Carafiban may potentially be used for chronic treatment and prophylaxis of thrombotic diseases in humans.
Status:
Investigational
Source:
NCT04679870: Phase 2 Interventional Active, not recruiting Myelofibrosis
(2021)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Showing 49091 - 49100 of 55039 results