U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 471 - 480 of 2243 results

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

GSK2606414 is an orally bioavailable, potent, selective inhibitor of PERK. The drug may serve as a potential treatment for cancer and neurodegenerative diseases associated with the accumulation and aggregation of misfolded disease-specific proteins in the brain. GSK2606414 demonstrated good results on a mouse model of prion disease.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)