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Development Status
Other
2,566
Investigational
628
US Approved Rx
460
Possibly Marketed Outside US
435
US Previously Marketed
171
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Primary Target
DNA
69
Dihydrofolate reductase
32
Tubulin
26
NF-kappa B signaling pathway
24
Dopamine D2 receptor
22
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Highest Phase
Approved
699
Phase II
109
Phase III
67
Phase I
59
Not Provided
28
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Approval Year
Unknown
3,421
1921
66
1994
36
1996
27
1995
25
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Condition
Unknown
128
Hypertension
75
Cancer
60
Non-small cell lung cancer
56
Breast cancer
45
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Treatment Modality
Primary
901
Palliative
103
Curative
101
Preventing
101
Diagnostic
48
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CNS Activity
CNS Active
332
CNS Penetrant
270
CNS Non-penetrant
117
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Originator
Eli Lilly
24
Cronstedt, A.F.
19
Merck
19
Novartis
18
Takeda Pharmaceutical
17
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Substance Class
Chemical
3,486
Structurally Diverse
326
Protein
311
Mixture
86
Polymer
63
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INN Stem
Chemical substance(-ine)
13
Monoclonal antibodies(-mab)
8
Peptides and glycopeptides(-tide)
4
Tyrosine-kinase inhibitors(-tinib)
2
Antiviral drug(-vir)
1
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GInAS Tag
KEW
30
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Code System
FDA UNII
4,305
CAS
3,681
PUBCHEM
3,421
EPA CompTox
2,734
ECHA (EC/EINECS)
1,406
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Protein Type
ENZYME
39
MONOCLONAL ANTIBODY
32
RECEPTOR
29
PEPTIDE
27
CYTOKINE
7
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ATC Level 1
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
84
NERVOUS SYSTEM
57
CARDIOVASCULAR SYSTEM
50
ALIMENTARY TRACT AND METABOLISM
43
ANTIINFECTIVES FOR SYSTEMIC USE
31
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ATC Level 2
ANTINEOPLASTIC AGENTS
67
OPHTHALMOLOGICALS
26
PSYCHOANALEPTICS
17
PSYCHOLEPTICS
15
ANTIBACTERIALS FOR SYSTEMIC USE
14
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
26
ANTIMETABOLITES
15
ANTIDEPRESSANTS
13
ALL OTHER THERAPEUTIC PRODUCTS
11
ANTIINFECTIVES
11
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ATC Level 4
Other antineoplastic agents
13
Dihydropyridine derivatives
10
Adrenergic and dopaminergic agents
7
Antibiotics
7
Detoxifying agents for antineoplastic treatment
7
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Substance Form
Principal Form
3,581
Salts, Hydrates, Esters, etc.
724
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Matches
20 fields
Approximate Matches
2239
Any Name
2234
Standardized Name
1127
Reference Text / Citation
487
Display Name
201
Reference URL
131
Related Substance Name
77
Organism Author
70
Note
50
Relationship Comments
48
Mixture Component Name
29
Code Literal
24
Code Comments
19
root_modifications_structuralModifications_molecularFragment_refPname
17
WIKIPEDIA
15
Code URL
14
root_modifications_structuralModifications_residueModified
14
Protein Structural Modification Residue
8
ALANWOOD
6
Structure Stereo Comments
4
Protein Structural Modification Substance Name
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