U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 421 - 430 of 11247 results

Status:
Investigational
Source:
INN:tematropium metilsulfate
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Tematropium, a muscarinic acetylcholine receptor antagonist that was studied as an antiasthmatic agent. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:razpipadon [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
JAN:PROFLUTHRIN [JAN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
JAN:EZ-EMPENTHRIN [JAN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Status:
Investigational
Source:
NCT00229437: Phase 2 Interventional Completed Diabetic Neuropathies
(2005)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN:SCOPAFUNGIN [USAN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Scopafungin (also known as GE4800) is an inhibitor of oxidative phosphorylation in mitochondria. Scopafungin also inhibits, in vitro, a variety of pathogenic fungi, yeasts, and gram-positive bacteria.
Status:
Investigational
Source:
NCT02332720: Phase 2 Interventional Completed Hepatitis C
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Ruzasvir (previously known as MK-8408) was developed as a nonstructural protein 5A (NS5A) inhibitor for the treatment of hepatitis C and hepatitis C infection. Ruzasvir successfully completed phase II clinical trial for combination therapy. The obtained results have shown that ruzasvir in combination with uprifosbuvir was highly effective and well-tolerated in participants infected with hepatitis C virus genotypes GT1, GT2, GT4, GT5, and GT6, with a lower efficacy in GT3-infected persons.
Status:
Investigational
Source:
NCT03959527: Phase 3 Interventional Completed Gonorrhea
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Zoliflodacin (also known as AZD0914 or ETX0914) is a spiropyrimidinetrione with activity against bacterial type II topoisomerases that inhibits DNA biosynthesis and results in accumulation of double-strand cleavages in bacteria. This drug is being a DNA gyrase inhibitor, targeting Neisseria gonorrhoeae and is currently in phase II clinical trial in adults to treat uncomplicated urogenital gonorrhea.
Status:
Investigational
Source:
NCT01597739: Phase 2 Interventional Completed Arthritis, Rheumatoid
(2012)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:theophylline ephedrine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Theophylline ephedrine is a pharmacologically active salt useful for the treatment of obstructive ventilatory disorders. Theophylline / Ephedrine is used for Wheezing, Shortness of breath, Chest tightness, Interruption of breathing in newborns, Mild and chronic bronchial asthma, Low blood pressure and other conditions.