U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 4271 - 4280 of 4326 results

Ziconotide (PRIALT; SNX-111) is a neuroactive peptide, which was approved by FDA in 2004 for the management of severe chronic pain in adult patients for whom intrathecal therapy is warranted, and who are intolerant of or refractory to other treatment, such as systemic analgesics, adjunctive therapies, or intrathecal morphine. Ziconotide acts as a selective N-type voltage-gated calcium channel blocker, which leads to a blockade of excitatory neurotransmitter release from the primary afferent nerve terminals.
Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.
nucleic acid
Status:
Investigational
Source:
INN:cobomarsen [INN]
Source URL:

Class:
NUCLEIC ACID

nucleic acid
Status:
Investigational
Source:
INN:zilebesiran [INN]
Source URL:

Class:
NUCLEIC ACID

nucleic acid
Status:
Investigational
Source:
INN:olezarsen [INN]
Source URL:

Class:
NUCLEIC ACID

Showing 4271 - 4280 of 4326 results