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Restrict the search for
tranexamic acid
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sodium thiophosphate (or sodium monothiophosphate) a biochemical reagent, a specific inhibitor of protein tyrosine phosphatase and a competitive inhibitor of alkaline phosphatase. Thiophosphate was effective in inducing apoptosis in some leukemia cell lines including CEM and K562 and a lymphoma cell line, Raji. In addition, monothiophosphate entered intracellular nucleotide pools and served as an effective precursor for the phosphorylation of nuclear proteins in vivo.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Tris(2-carboxyethyl)phosphine or TCEP is a potent, versatile, odorless, thiol-free reducing agent with broad application to protein and other research involving reduction of disulfide bonds. Because TCEP does not contain thiols, it does not have to removed from solutions before performing reactions involving maleimide labeling or cross-linking reagents. TCEP may be used as a substitute for DTT or 2-mercaptoethanol (2-ME) in reducing sample loading buffer for SDS-PAGE. One strategy for labeling antibodies involves reducing disulfide bonds in the hinge region of IgG molecules without also reducing those connecting heavy and light chains.
