Ritalinic acid is an inactive, major metabolite of methylphenidate, a schedule II drug in the United States commonly used as a psychostimulant drugs methylphenidate and ethylphenidate. The elimination half-life of methylphenidate is relatively short (approximately 2 hours); therefore it is also available in extended release (ER) forms. The main metabolite is ritalinic acid, and the methylphenidate metabolites are mostly excreted in urine.

Gabazine (SR-95531) is a selective GABAA receptors antagonist, which does not have any role in medicine, but is used in scientific experiments as the allosteric inhibitor of channel opening for the GABAA receptor.