U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 3051 - 3060 of 4709 results

mixture
Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(12)(iv)(C) laxative:stimulant laxative aloe ingredients (aloe, aloe extract, aloe flower extract)
Source URL:
First approved in 1976

Class:
MIXTURE

mixture
Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(20) weight control plantago seed
Source URL:
First approved in 1949
Source:
Hydrocil Instant Dietary Fiber Supplement by NUMARK BRANDS, INC
Source URL:

Class:
MIXTURE

mixture
Status:
US Previously Marketed
Source:
Diaparene Chloride by Homemaker's (Breon)
(1947)
Source URL:
First approved in 1947
Source:
Diaparene Chloride by Homemaker's (Breon)
Source URL:

Class:
MIXTURE

mixture
Status:
US Previously Marketed
Source:
Cresol U.S.P.
(1921)
Source URL:
First marketed in 1921

Class:
MIXTURE

mixture
Status:
US Previously Marketed
Source:
aluminium magnesium silicate
(1921)
Source URL:
First marketed in 1921
Source:
aluminium magnesium silicate
Source URL:

Class:
MIXTURE

mixture
Status:
Possibly Marketed Outside US

Class:
MIXTURE

mixture
Status:
Possibly Marketed Outside US

Class:
MIXTURE

QS-21 is a purified soapbark tree (Quillaja saponaria) extract that enhances the ability of the immune system to respond to vaccine antigens. QS-21 is a promising adjuvant candidate for use in humans due to the ease of purification, its improved safety profile, and its ability to enhance cellular and humoral immunogenicity. The mechanism of action of QS-21 was speculated to be similar to QA, forming complexes with cholesterol that intercalate into the cell membrane lipids. This intercalation creates pores in the membrane to accelerate the uptake of a co-delivered antigen by the antigen presenting cells. Multiple clinical trials using QS-21 as an adjuvant, demonstrated satisfactory safety profiles and enhanced immunogenicity in immunocompromised volunteers
mixture
Status:
Possibly Marketed Outside US
Source:
NCT04590521: Phase 4 Interventional Completed HPV Infection
(2022)
Source URL:

Class:
MIXTURE

Showing 3051 - 3060 of 4709 results