U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 21 - 30 of 276 results

Status:
Investigational
Source:
INN:elinzanetant [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
J Reprod Med. Dec 1999;44(12):1012-20.: Not Applicable Human clinical trial Completed N/A
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Equilin is one of the active components of estrogens used in estrogen replacement therapy. This compound is used as a sulfate conjugate in drug Premarin. Equili is an inhibitor of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1), a key enzyme responsible for elevated levels of 17beta-estradiol (E2) in breast tumor tissues. Thus equilin reduce the E2 levels in breast tissues and hence the reduce risk of estrogen-dependent breast cancer.
Status:
Investigational
Source:
INN:doxibetasol
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Doxybetasol is the corticosteroid. It is an impurity of Betamethasone, which is a glucocorticoid used as an anti-inflammatory agent. Doxybetasol also has anti-inflammatory and anti-allergic properties.
Status:
Investigational
Source:
INN:alestramustine
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Alestramustine is the l-alanine ester form of estramustine, a combination of the nitrogen mustard normustine coupled via a carbamate to estradiol, with antineoplastic activity. Upon conversion of alestramustine to estramustine, estramustine binds to microtubule-associated proteins (MAPs) and beta tubulin, thereby interfering with microtubule dynamics and leading to microtubule disassembly and cell cyle arrest. Due to the estrogen moiety, this agent is able to selectively bind to and be taken up by estrogen receptor-positive cells.
Status:
Investigational
Source:
USAN:FLUPREDNISOLONE VALERATE [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

The information related to the biological or pharmacological application of fluprednisolone valerate is absent.
Status:
Investigational
Source:
USAN:PREDNIVAL [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Prednival is prednisolone derivative patented by Francesco Vismara, Societa per Azioni as anti-inflammatory and progestational agent.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)