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Development Status
Other
1,845
Possibly Marketed Outside US
237
Investigational
215
US Approved Rx
168
US Previously Marketed
79
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Primary Target
Glucocorticoid receptor
32
Progesterone receptor
21
Gonadotropin-releasing hormone receptor
16
Cyclooxygenase-2
15
Cyclooxygenase-1
13
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Highest Phase
Approved
283
Phase II
19
Not Provided
15
Phase III
9
Phase I
4
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Approval Year
Unknown
2,172
1921
41
2020
22
2010
12
2012
12
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Condition
Unknown
66
Rheumatoid arthritis
26
Pain
18
Hypertension
15
Pregnancy
14
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Treatment Modality
Primary
287
Preventing
68
Palliative
62
Curative
53
Diagnostic
19
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CNS Activity
CNS Active
102
CNS Penetrant
79
CNS Non-penetrant
34
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Originator
Pfizer
16
Merck Sharp & Dohme
11
Bayer
8
Syntex
7
Sanofi-Aventis
6
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Substance Class
Chemical
2,430
Protein
60
Mixture
47
Polymer
38
Concept
4
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INN Stem
Chemical substance(-ine)
4
Prostaglandin analogue(-prost-)
1
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Code System
FDA UNII
2,579
CAS
2,442
PUBCHEM
2,422
EPA CompTox
1,769
ECHA (EC/EINECS)
838
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Protein Type
PEPTIDE
20
ENZYME
3
HORMONE
2
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ATC Level 1
CARDIOVASCULAR SYSTEM
15
SENSORY ORGANS
14
DERMATOLOGICALS
13
ALIMENTARY TRACT AND METABOLISM
12
BLOOD AND BLOOD FORMING ORGANS
11
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ATC Level 2
OPHTHALMOLOGICALS
13
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
11
ANTITHROMBOTIC AGENTS
7
CORTICOSTEROIDS FOR SYSTEMIC USE
7
OTOLOGICALS
7
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ATC Level 3
CORTICOSTEROIDS, PLAIN
11
AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
7
ANTITHROMBOTIC AGENTS
7
CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
7
CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
7
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ATC Level 4
Corticosteroids, potent (group III)
8
Glucocorticoids
7
Corticosteroids
6
Corticosteroids and antiinfectives in combination
6
Corticosteroids, plain
6
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Substance Form
Principal Form
2,001
Salts, Hydrates, Esters, etc.
578
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