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4-Hydroxy-4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexen-1-one, (4S,3R)-(E)-(±)- (Blumenol A) is a major secondary metabolite initially isolated from the leaves of Annona glabra L. (Annonaceae), commonly known as pond apple, which is a tropical tree distributed mainly in the Americas and in Southeast Asia, and used in traditional medicine as an insecticide and a parasiticide. Blumenol A was reported to display inhibitory activity against a panel of human solid tumor cell lines