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Development Status
Other
1,692
Investigational
246
Possibly Marketed Outside US
171
US Approved Rx
73
US Previously Marketed
37
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Primary Target
Voltage-gated L-type calcium channel
12
Acetylcholinesterase
11
Adrenergic receptor alpha-1
11
Beta-2 adrenergic receptor
11
Serotonin 1a (5-HT1a) receptor
9
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Highest Phase
Approved
153
Not Provided
12
Phase III
12
Phase II
10
Phase I
6
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Approval Year
Unknown
2,047
1921
8
2009
7
2013
7
2020
7
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Condition
Unknown
35
Hypertension
24
Pain
12
Osteoarthritis
10
Rheumatoid arthritis
10
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Treatment Modality
Primary
149
Curative
42
Preventing
31
Palliative
23
Diagnostic
17
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CNS Activity
CNS Active
69
CNS Penetrant
32
CNS Non-penetrant
21
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Originator
AstraZeneca
7
Bayer
6
Parke, Davis, & Co.
6
Imperial Chemical Industries
5
Merck
5
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Substance Class
Chemical
2,043
Protein
83
Polymer
34
Structurally Diverse
33
Mixture
26
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INN Stem
Chemical substance(-ine)
9
Monoclonal antibodies(-mab)
5
Chimeric antibody that responds to more than one antigen(-ximab)
1
Tyrosine-kinase inhibitors(-tinib)
1
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GInAS Tag
KEW
1
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Code System
FDA UNII
2,236
CAS
2,103
PUBCHEM
2,001
EPA CompTox
1,703
ECHA (EC/EINECS)
982
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Protein Type
MONOCLONAL ANTIBODY
20
PEPTIDE
8
BISPECIFIC ANTIBODY
3
CYTOKINE
3
ENZYME
3
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ATC Level 1
CARDIOVASCULAR SYSTEM
19
NERVOUS SYSTEM
16
ALIMENTARY TRACT AND METABOLISM
9
DERMATOLOGICALS
9
MUSCULO-SKELETAL SYSTEM
9
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ATC Level 2
CALCIUM CHANNEL BLOCKERS
8
OPHTHALMOLOGICALS
8
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
7
ANALGESICS
6
PSYCHOANALEPTICS
6
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ATC Level 3
SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
8
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
7
ANTIDEPRESSANTS
5
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
5
ANTIFUNGALS FOR TOPICAL USE
4
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ATC Level 4
Dihydropyridine derivatives
8
Antiinflammatory preparations, non-steroids for topical use
5
Adrenergic and dopaminergic agents
4
Other antifungals for topical use
4
Anti-androgens
3
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Substance Form
Principal Form
1,998
Salts, Hydrates, Esters, etc.
238
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