U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 191 - 200 of 19755 results

Status:
Investigational
Source:
NCT04318626: Phase 2 Interventional Recruiting Post-stroke Cognitive Impairment
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


THK-5351 is a novel tau-binding quinoline derivative used as precursors of 18F-labeled radiotracer THK-5351 F-18.
Status:
Investigational
Source:
INN:bifepramide [INN]
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Bifepramide, (+)- belong to the class of parasympatholytic agents that reduce the activity of the parasympathetic nervous system.
Status:
Investigational
Source:
NCT00562237: Phase 1 Interventional Terminated Healthy Subjects
(2007)
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
NCT04713319: Early Phase 1 Interventional Completed Healthy Participants
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:donitriptan
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Donitriptan hydrochloride (F 11356) was developed by Pierre Fabre as a brain penetrant 5-HT1B/1D agonist. Which inhibits capsaicin-induced external carotid vasodilation and produces selective carotid vasoconstriction in various animal species. In January 2001, donitriptan had completed phase I trials for migraine and was scheduled to enter phase II development, but before development in phase II, this drug was discontinued.
Status:
Investigational
Source:
NCT03257592: Phase 1 Interventional Terminated Schizophrenia
(2010)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT04340258: Phase 1/Phase 2 Interventional Active, not recruiting HNSCC
(2021)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT04599140: Phase 1/Phase 2 Interventional Recruiting Metastatic Colon Adenocarcinoma
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT01225939: Phase 1 Interventional Completed Type 2 Diabetes Mellitus
(2010)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT01652742: Phase 1 Interventional Completed Healthy
(2012)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)