U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1941 - 1950 of 4710 results

CYCLAZOSIN HYDROCHLORIDE is a quinazoline derivative pharmacologically characterized as putative a1B-adrenoceptor antagonist.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

LDC1267 preferentially inhibits TAM tyrosine kinase receptors Tyro3, Axl and Mer at low nanomolarity. LDC1267 conferred therapeutic potential, efficiently enhancing anti-metastatic natural killer (NK) cells activity. In vivo the compound markedly reduced murine mammary cancer and melanoma metastases dependent on NK cells.
Phenanthridinone, an isoquinoline derivative, is a potent poly(ADP-ribose)polymerase 1 inhibitor. It could be considered as a potent immunomodulator, and also as the prototype of a new class of adjuncts in cancer chemotherapy.

Showing 1941 - 1950 of 4710 results