U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 171 - 180 of 224 results

Status:
Investigational
Source:
INN:monalazone disodium [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Monalazone is a sulfonylbenzoic acid derivative used as vaginal disinfectant or antiseptic and spermicidal contraceptive.
Status:
Investigational
Source:
INN:laurolinium acetate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

LAUROLINIUM, a quaternary ammonium compound, is a cationic antimicrobial agent. It has a broad spectrum of activity against Gram‐positive and Gram‐negative bacteria, fungi, and protozoan Trichomonas vaginalis. It is suitable for use in the treatment of local infections, for the sterilization of skin areas and for general antiseptic purposes.
Status:
Investigational
Source:
INN:penoctonium bromide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Penoctonium, a chemotherapeutic agent was used in microbial studies. However, information about the further development of this compound is not available.
Status:
Investigational
Source:
INN:sepazonium chloride
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Sepazonium was studied as a topical anti-infective drug. However, information about the current use of this agent is not available.
Status:
Investigational
Source:
NCT00612508: Not Applicable Interventional Completed Contraceptive Usage
(2007)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Dofamium is the antiseptic agent. It was used for the water sterilization.
Status:
Investigational
Source:
INN:opratonium iodide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:pirtenidine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Pirtenidine is the antimicrobial agent. Pirtenidine was found to be highly efficacious against oral plaque-forming microorganisms. Adherence of Candida spp. to buccal epithelial cells in vitro was significantly reduced after both short- and long-term periods of yeast exposure to sub-inhibitory concentrations of pirtenidine. The drug was shown to cause extensive leakage of cytoplasmic contents from the Candida albicans cells which was correlated with morphological and ultrastructural changes in the yeast. Pirtenidine affects the lipids and sterol composition of C. albicans.
Status:
Investigational
Source:
INN:octafonium chloride
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Octafonium (or octaphonium) was used as an antiseptic. Information about the current use of this drug is not available.
Status:
Investigational
Source:
INN:halopenium chloride
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Halopenium was studied as an antibacterial and antifungal agent.
Status:
Investigational
Source:
INN:sodium timerfonate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Thimerfonate is a alkyl mercuric derivative with germicidal activity.

Showing 171 - 180 of 224 results