Mecetronium etilsulfate (MES) is a detergent and belongs to the group of surface-active ingredients. MES along with propan-2-ol and propan-1-ol is an ingredient of rub-in hand disinfectants. The antimicrobial contribution of MES in hand rubs is questionable. MES locks on the outermost layer of the skin (stratum corneum) for sustained bacterial reduction as long as 3 to 5 hours.

Benzoxonium is a quaternary ammonium compound with antibacterial, antiviral, and antimycotic activity. It can be used in topical disinfection, disinfection of surgical instruments, inhibition of plaque formation, and in veterinary products.

Enisamium (4-(benzylcarbamoyl)-1-methylpyridinium iodide) is an isonicotinic acid derivative, that used as an antiviral agent in Russia. Enisamium suppresses the effect of influenza viruses and other pathogens of acute respiratory viral infections due to a direct inhibitory effect on the penetration of viruses through the cell membrane. Enisamium has interferonogenic properties, promotes an increase in the concentration of endogenous interferon (interferon alfa and gamma) in blood plasma by 3-4 times.

Alafosfalin is a phosphonodipeptide with significant activity as an antibacterial agent and as a potentiator of beta-lactam antibiotics. Alafosfalin shows good activity both in vitro and in vivo, particularly against Enterobacteriaceae. The compound acts by interfering with bacterial cell wall biosynthesis and also potentiates the activity of beta-lactam antibiotics. Alafosfalin was found to be highly active against Escherichia coli and moderately active against Serratia, Klebsiella, Enterobacter, and Citrobacter, but less active against gram-positive organisms than were beta-lactams such as cephazolin or ampicillin and inactive against indole-positive Proteus, Pseudomonas, and Acinetobacter.

Pipemidic Acid is a quinolone antibacterial agent. It’s used in the treatment of urinary tract infections, recidive cystitis, prolongation of the therapy of pyelonephritis (prolonged therapy at patients with tendency to recidives. It belongs to DNA Gyrase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibacterial pharmacological group. Pipemidic acid is contraindicated at conditions of proved hypersensitivity, severe renal and hepatic insufficiency, cirrhosis of the liver, porphyria, diseases of the central nervous system (epilepsy and neurological conditions with low level for convulsions). Pipemidic acid is contraindicated at children and adolescents at growing phase.

Cholinergic anthelmintic, Thenium is used against dog and cat hookworms.

Enviroxime (LY 122772 or 2-amino-1-(isopropyl sulphonyl)-6-benzimidazole phenyl ketone oxime) is an benzimidazole antiviral agent. Enviroxime inhibits the replication of rhinoviruses and enteroviruses, additionally it impedes the replication of the hepatitis C virus. Enviroxime targets the 3A coding region of rhinovirus and poliovirus. Enviroxime is able to inhibit host phosphatidylinositol 4-kinase III.

Thiamphenicol is a broad-spectrum antibiotic, which is active against gram-positive and gram-negative organisms. The drug is marketed in Asia and Latin America for the treatment of various infections, including sexually transmitted diseases. As many phenicols, thiamphenicol inhibits the protein synthesis in bacterias by binding to 23S ribosomal subunit. In Europe and USA the drug is used in a veterinary practice.

Beclabuvir (previously known as BMS-791325), a potent, non-nucleoside inhibitor of the HCV NS5B RNA polymerase. In combination with daclatasvir and asunaprevir drug participates in clinical trials phase III for patients infected with HCV genotype 1, which is the most common genotype worldwide. Recently published data has shown that this combination achieved very high rates of viral eradication.

Cefteram is a semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefteram pivoxil. The mechanism of action of cefteram is inhibition of bacterial cell wall synthesis. Cefteram exerts its bactericidal activity by strongly binding to penicillin-binding protein (PBP) 3, 1A, and 1Bs. The drug is available in Japan and is used for the treatment of bacterial infections.