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Development Status
US Approved Rx
70
Investigational
52
Possibly Marketed Outside US
20
US Previously Marketed
10
Designated
5
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Primary Target
DNA
6
Vascular endothelial growth factor receptor 2
5
Histone deacetylase 1
4
Histone deacetylase 2
4
Platelet-derived growth factor receptor beta
4
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Highest Phase
Approved
71
Phase III
24
Phase II
13
Not Provided
1
Phase I
1
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Approval Year
Unknown
70
2007
5
2009
5
2003
4
2008
4
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Condition
Breast cancer
10
Multiple myeloma
8
Ovarian cancer
7
Non-small cell lung cancer
6
Acute myeloid leukemia
5
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Treatment Modality
Primary
96
Palliative
11
Curative
9
Preventing
7
Secondary
5
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CNS Activity
CNS Penetrant
48
CNS Active
22
CNS Non-penetrant
4
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Originator
Novartis
3
Agouron Pharmaceuticals
2
AstraZeneca
2
Bayer
2
Bristol-Myers Squibb
2
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Substance Class
Chemical
121
Protein
30
Polymer
3
Mixture
2
Nucleic Acid
1
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Code System
EU-Orphan Drug
157
FDA UNII
157
CAS
156
NCI_THESAURUS
152
DRUG BANK
140
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Protein Type
MONOCLONAL ANTIBODY
12
COAGULATION FACTOR
1
ENZYME
1
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ATC Level 1
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
34
ALIMENTARY TRACT AND METABOLISM
6
CARDIOVASCULAR SYSTEM
6
SENSORY ORGANS
6
VARIOUS
5
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ATC Level 2
ANTINEOPLASTIC AGENTS
24
IMMUNOSUPPRESSANTS
7
OPHTHALMOLOGICALS
6
ALL OTHER THERAPEUTIC PRODUCTS
3
ANTIBACTERIALS FOR SYSTEMIC USE
3
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
21
IMMUNOSUPPRESSANTS
7
ALL OTHER THERAPEUTIC PRODUCTS
3
ANTIINFECTIVES
3
IMMUNOSTIMULANTS
3
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ATC Level 4
Other antineoplastic agents
10
Protein kinase inhibitors
6
Monoclonal antibodies
4
Antidotes
3
Antihypertensives for pulmonary arterial hypertension
2
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Substance Form
Principal Form
116
Salts, Hydrates, Esters, etc.
41
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