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National Institutes of Health
NCATS
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Development Status
Other
8,871
Possibly Marketed Outside US
585
Investigational
270
US Approved Rx
180
US Previously Marketed
133
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Primary Target
Oxidative Stress
21
Peroxisome proliferator-activated receptor gamma
16
Cyclooxygenase-2
15
Farnesyl diphosphate synthase
14
GABA-A receptor; anion channel
14
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Highest Phase
Approved
368
Not Provided
32
Phase III
26
Phase II
22
Phase I
18
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Approval Year
Unknown
9,311
1921
92
2024
47
2013
36
2020
35
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Condition
Unknown
193
Cancer
49
Breast cancer
20
Type 2 diabetes mellitus
20
Acne
19
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Treatment Modality
Primary
375
Diagnostic
94
Palliative
86
Preventing
80
Curative
65
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CNS Activity
CNS Penetrant
118
CNS Active
93
CNS Non-penetrant
69
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Originator
Guerbet
10
Ciba-Geigy
7
Chevreul, M.E.
6
Khaunma, R.A.
6
Moissan, H.
5
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Substance Class
Chemical
9,530
Protein
177
Mixture
168
Polymer
102
Nucleic Acid
88
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INN Stem
Peptides and glycopeptides(-tide)
16
Chemical substance(-ine)
2
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Code System
FDA UNII
10,064
CAS
9,389
PUBCHEM
9,228
EPA CompTox
6,371
ECHA (EC/EINECS)
2,855
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Protein Type
PEPTIDE
39
RECEPTOR
15
ENZYME
12
TRANSPORTER
7
MONOCLONAL ANTIBODY
5
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ATC Level 1
ALIMENTARY TRACT AND METABOLISM
40
VARIOUS
39
DERMATOLOGICALS
25
ANTIINFECTIVES FOR SYSTEMIC USE
24
MUSCULO-SKELETAL SYSTEM
24
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ATC Level 2
CONTRAST MEDIA
24
ANTIBACTERIALS FOR SYSTEMIC USE
18
OPHTHALMOLOGICALS
16
DRUGS FOR TREATMENT OF BONE DISEASES
14
VITAMINS
12
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ATC Level 3
X-RAY CONTRAST MEDIA, IODINATED
19
DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
14
ANTITHROMBOTIC AGENTS
10
ANTIINFECTIVES
8
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
8
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ATC Level 4
Bisphosphonates
9
Watersoluble, hepatotropic X-ray contrast media
9
Bisphosphonates, combinations
7
Watersoluble, nephrotropic, high osmolar X-ray contrast media
7
Antiinfectives
6
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Substance Form
Principal Form
9,343
Salts, Hydrates, Esters, etc.
721
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