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Search results for amphotericin root_codes_comments in Code Comments (approximate match)
Status:
Designated
Source:
FDA ORPHAN DRUG:18887
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
B-Trisaccharide belongs to the class of organic compounds known as fatty acyl glycosides of mono- and disaccharides. B-Trisaccharide in blood group B is excreted when an individual is given Galactose. The B-trisaccharide was the only oligosaccharide detected in plasma after galactose administration to a blood-group-B secretor individual. The structure of the branched blood group B trisaccharide alone has been studied both by X-ray crystallography and by NMR.
Status:
Designated
Source:
FDA ORPHAN DRUG:18086
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
A-TRISACCHARIDE (or Blood group A trisaccharide), a core antigen fragment in ABO blood group system. It was found to be a major urinary carbohydrate depending on diet and blood type.
Status:
Designated
Source:
FDA ORPHAN DRUG:269808
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
TH9402 is a dibrominated rhodamine derivative and potent photosensitizer and useful in photodynamic therapy. TH9402 preferentially localizes in mitochondria and when exposed to 500- to 600-nm wavelength visible light delivered through the Theralux device, it becomes highly cytotoxic through oxidative damage. TH9402 eradicates multiple myeloma (MM) and BC cell lines, while sparing more than 50% of normal pluripotential blood stem cells from healthy volunteers. TH9402 offers an excellent potential as an ex vivo photodynamic purging agent for autologous transplantation in multiple myeloma and breast cancer treatment. TH9402 photodynamic-cell-therapy process conditions recognized as safe for normal human haematopoietic stem cells and progenitors demonstrated the efficacy of the purging procedure on various leukaemias.
Benzyl butyl phthalate is used as a plasticizer for polyvinyl chloride in vinyl floor tiles, vinyl foam and carpet backing, in cellulosic resins, and as an organic intermediate. It has also been used as a solvent and fixative in perfume. It is a colorless and odorless organic chemical. Exposure to benzyl butyl phthalate occurs during its production and use as a plasticizer, mainly in polyvinyl chloride products. It has been detected at low levels in indoor air, water, and a few foods. Benzyl butyl phthalate is classified as a substance toxic to reproduction. It demonstrated estrogen and anti-androgen activity. Prenatal exposure to phthalates could lead to smaller penis size and incomplete descent of testicles in baby boys.