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amphotericin b
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Osajin is the major bioactive isoflavone present in the fruit of Maclura pomifera, commonly referred to as the Osage orange. Osajin have potent cardioprotective effects in perfused rat hearts and kidney subjected to global ischemia and reperfusion. Its effects may be mediated through the inhibition of lipid peroxidation. Osajin can antagonize myocardial injury induced by I/R through inhibiting oxidative stress. Osajin had a noticeable inhibition of AChE with IC(50) values of 2.239 mM.
![Structure of 1-(tert-Butyl)-3-((5-chloro-3-(chloromethyl) pyridin-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one](/img/55d00aa9-8337-4c08-9d44-d54d8a9b7246.svg?size=200&context=oamidqsxrf)
![Structure of (4aS,9bR)-6-Bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole](/img/87019b13-acd0-4451-a3de-f10311d554f7.svg?size=200&context=oamidqsxrf)