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glycerol phenylbutyrate
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Glyceryl 2-linoleate is a fatty acid derivative. It inhibits monoacylglycerol lipase and fatty acid amide hydrolase activity. Glyceryl 2-linoleate enhanced a 2-Arachidonoyl-glycerol inhibition of tumor necrosis factor alpha production in murine macrophages when applied with 2-Arachidonoyl-glycerol. Initially, it was found that Glyceryl 2-linoleate potentiated the apparent binding of 2-Arachidonoyl-glycerol to cannabinoid receptors CB1 and CB2. However, later research revealed that in no case do the lipid Glyceryl 2-linoleate acts as entourage compounds for 2-Arachidonoyl-glycerol. Increase in Glyceryl 2-linoleate plasma concentrations was observed in cocaine subjects diagnosed with psychiatric comorbidity.
