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Search results for telotristat root_names_name in Any Name (approximate match)
Status:
Possibly Marketed Outside US
First approved in 2008
Source:
BP Cleansing Wash by Acella Pharmaceuticals, LLC
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Disodium oleic monoethanolamine sulfosuccinate is excipient used in pharmaceutical and cosmetic as preservative and as non-toxic and non-irritating capsulated laundry detergent.
Status:
Possibly Marketed Outside US
Source:
NCT03915535: Phase 4 Interventional Terminated Healthy Athletes
(2019)
Source URL:
First approved in 2007
Source:
DHA by Exeltis USA, Inc
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Doconexent (Docosahexaenoic acid, DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina. DHA is widely used as a food supplement, and is beleived to support healthy brain development in young childred, prevent cardiovascular disease and cognitive decline during Alzheimer's disease. Most of these claims, however, were not supported by clinical trials. DHA spray is used as a tanner.
Status:
Possibly Marketed Outside US
First approved in 2000
Source:
NADA141036
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Pirlimycin is an antibiotic which was approved in the US and Europe for the treatment of subclinical mastitis in lactating dairy cattle associated with common mastitis pathogens, mostly Gram-positive bacterias. The drug exerts its action by binding to the 50S ribosomal subunit, therefore hindering the aminoacyl-tRNA binding and inhibiting the peptidyltransferase reaction, which interferes with protein synthesis within the bacteria.
Status:
Possibly Marketed Outside US
First approved in 2000
Source:
NADA141036
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Pirlimycin is an antibiotic which was approved in the US and Europe for the treatment of subclinical mastitis in lactating dairy cattle associated with common mastitis pathogens, mostly Gram-positive bacterias. The drug exerts its action by binding to the 50S ribosomal subunit, therefore hindering the aminoacyl-tRNA binding and inhibiting the peptidyltransferase reaction, which interferes with protein synthesis within the bacteria.
Status:
Possibly Marketed Outside US
Source:
M018
(1999)
Source URL:
First approved in 1999
Source:
M018
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M018
(1999)
Source URL:
First approved in 1999
Source:
M018
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M018
(1999)
Source URL:
First approved in 1999
Source:
M018
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
NCT04162834: Phase 4 Interventional Completed Kidney Cancer
(2019)
Source URL:
First approved in 1995
Source:
Papaverine Hydrochloride by American Regent, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. Papaverine is a vasodilating agent. Papaverine is used for the treating certain conditions that are accompanied by smooth muscle spasms (eg, blood vessel, urinary, gallbladder, or intestinal spasm). Papaverine is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine are exerted on cardiac and smooth muscle. Like qathidine, Papaverine acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine is practically devoid of effects on the central nervous system. Papaverine relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries. Papaverine is a potent, specific inhibitor of PDE10A. Papaverine for treatment of erectile dysfunction (ED) is excluded from coverage.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333D
(2015)
Source URL:
First approved in 1995
Source:
M017
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID (HEDTA) is used in cosmetics and care products. It’s a chelating agent, which in combination with selenium was effective in reducing the concentration of Al and level of DNA damage. In addition, experiments with rodents have shown that combination of HEDTA and propolis preserved histological features, mitigated oxidative stress and improved liver, kidney, and brain functions more profoundly.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333D
(2015)
Source URL:
First approved in 1995
Source:
M017
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID (HEDTA) is used in cosmetics and care products. It’s a chelating agent, which in combination with selenium was effective in reducing the concentration of Al and level of DNA damage. In addition, experiments with rodents have shown that combination of HEDTA and propolis preserved histological features, mitigated oxidative stress and improved liver, kidney, and brain functions more profoundly.