U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1201 - 1210 of 1904 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Cedryl acetate is widely used as the aroma in daily chemicals (content less than 20%). It also can be used in food approved by FDA but not more than 1m/kg. It was shown, that cedryl acetate possesses α-glucosidase inhibitory activity.
Status:
Possibly Marketed Outside US
Source:
AQUACID-220 by Aqua Medica, S.A. de C.V.
(2020)
Source URL:
First approved in 2020
Source:
AQUACID-220 by Aqua Medica, S.A. de C.V.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Sodium acetate C-11 (C-11 acetate) Injection is a radiopharmaceutical commonly used for clinical studies with positron emission tomography (PET). It is used as a PET radiotracer for imaging cancer cells via incorporation into intracellular phosphatidylcholine membrane microdomains in cancer cells. Positron emission tomography using carbon-11 acetate (AC-PET) may help find local or distant metastases from prostate cancer. C-11 acetate is taken up in proportion to fatty acid synthesis. It is also taken up proportionally to myocardial blood flow, and therefore myocardial oxygen consumption. In rodents, there is clearance from all organs except the pancreas within one hour. Tumor uptake was clearly visible in 30 minutes. In humans, more than 80% of tracer is cleared from normal tissues within 20 minutes.It is taken up in cancer within the prostate and prostate cancer metastases, however, it has been reported that increased uptake can be seen in hyperplastic and benign prostate tissues. No urinary excretion is seen. No toxic effects have been demonstrated. The ongoing clinical trial NCT01530269 is studying how this imaging test may help influence the choice and extent of initial treatments, and subsequent treatments of prostate cancer.

Showing 1201 - 1210 of 1904 results