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National Institutes of Health
NCATS
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Development Status
Other
8,618
Investigational
1,038
Possibly Marketed Outside US
774
US Approved Rx
463
US Previously Marketed
262
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Primary Target
Histamine H1 receptor
88
Bacterial penicillin-binding protein
75
Muscarinic acetylcholine receptor M3
43
Voltage-gated L-type calcium channel
37
Muscarinic acetylcholine receptor M1
34
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Highest Phase
Approved
915
Phase II
92
Phase III
68
Not Provided
48
Phase I
43
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Approval Year
Unknown
10,111
2020
78
1921
50
2011
36
2012
30
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Condition
Unknown
162
Hypertension
74
Cancer
62
Pain
54
Asthma
40
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Treatment Modality
Primary
998
Curative
273
Palliative
178
Preventing
132
Diagnostic
42
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CNS Activity
CNS Active
417
CNS Penetrant
295
CNS Non-penetrant
127
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Originator
Pfizer
54
Merck
38
Bayer
25
Beecham Group
22
Eli Lilly
22
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Substance Class
Chemical
10,882
Mixture
205
Protein
75
Polymer
55
Structurally Diverse
15
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INN Stem
Chemical substance(-ine)
56
Tyrosine-kinase inhibitors(-tinib)
11
Antiviral drug(-vir)
6
Peptides and glycopeptides(-tide)
3
Prostaglandin analogue(-prost-)
1
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Code System
FDA UNII
11,238
CAS
10,786
PUBCHEM
10,536
EPA CompTox
7,305
ECHA (EC/EINECS)
2,699
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Protein Type
ENZYME
13
MONOCLONAL ANTIBODY CONJUGATE
13
RECEPTOR
5
PEPTIDE
4
BISPECIFIC ANTIBODY
1
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ATC Level 1
ANTIINFECTIVES FOR SYSTEMIC USE
74
NERVOUS SYSTEM
58
ALIMENTARY TRACT AND METABOLISM
46
RESPIRATORY SYSTEM
46
CARDIOVASCULAR SYSTEM
42
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
49
ANTIVIRALS FOR SYSTEMIC USE
22
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
21
ANTINEOPLASTIC AGENTS
18
ANTIHISTAMINES FOR SYSTEMIC USE
17
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ATC Level 3
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
37
DIRECT ACTING ANTIVIRALS
22
ANTIHISTAMINES FOR SYSTEMIC USE
17
OTHER ANTINEOPLASTIC AGENTS
15
SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
14
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ATC Level 4
Penicillins with extended spectrum
19
Dihydropyridine derivatives
14
Beta-lactamase sensitive penicillins
10
Xanthines
10
Antihistamines for topical use
8
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Substance Form
Principal Form
9,327
Salts, Hydrates, Esters, etc.
1,911
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dimethyl fumarate
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Matches
40 fields
Approximate Matches
10822
Standardized Name
10822
Any Name
2474
Note
2466
Display Name
771
Related Substance Name
405
Reference Text / Citation
78
Code Literal
63
Mixture Component Name
49
WIKIPEDIA
28
Code Comments
28
JECFA EVALUATION
21
Reference URL
17
Code URL
15
Monomer Substance Name
5
Relationship Comments
4
ALANWOOD
3
MANUFACTURER PRODUCT INFORMATION
2
WHO INTERNATIONAL PHARMACOPEIA
2
Protein Structural Modification Substance Name
2
root_modifications_structuralModifications_molecularFragment_refPname
Exact Matches
10
Related Substance Name
1
Display Name
1
Standardized Name
1
Code Literal
1
Any Name
1
LACTMED
1
Reference Text / Citation
1
WIKIPEDIA
Approximate Matches
10
Related Substance Name
2
Code Comments
2
Reference URL
2
Standardized Name
2
Any Name
1
Display Name
1
Code Literal
1
LACTMED
1
Reference Text / Citation
1
Note
1
WIKIPEDIA
1
Relationship Comments
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