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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
SANT-1 is antagonist of Smoothened (Smo), a distant relative of G protein-coupled receptors, mediates Hedgehog (Hh) signaling during embryonic development and can initiate or transmit ligand-independent pathway activation in tumorigenesis. It suppressed cancer cell viability, proliferation and colony formation.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Methylene di-t-butylcresol (GERI-BP002-A) is a hindered phenolic antioxidant and thermal stabilizer providing effective stabilization in adhesives, ABS, polyolefins, and other substrates. GERI-BP002-A is a novel inhibitor of SOAT (Acyl-CoA Cholesterol Acyltransferase (ACAT)) which is produced by Aspergillus fumigatus F93. GERI-BP002-A also exhibits antioxidant activity.
![Structure of N-[[3-(Aminomethyl)phenyl]methyl]carbamic acid](/img/5b96e432-3d95-4048-9d7b-e4751108db54.svg?size=200&context=bfgrlfyjtu)
![Structure of 2-(4-Phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide](/img/db6dc614-88e8-431f-a01c-4b75870986c3.svg?size=200&context=bfgrlfyjtu)
