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Development Status
Other
107,652
Possibly Marketed Outside US
10,255
Investigational
9,777
US Approved Rx
1,612
US Previously Marketed
1,444
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Primary Target
DNA
153
Dopamine D2 receptor
145
Apoptosis
123
GABA-A receptor; anion channel
114
Serotonin 2a (5-HT2a) receptor
112
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Highest Phase
Approved
3,294
Phase II
697
Phase III
386
Phase I
309
Not Provided
289
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Approval Year
Unknown
120,729
2020
647
2012
523
2013
515
1921
496
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Condition
Unknown
1,477
Cancer
395
Pain
281
Hypertension
243
Breast cancer
229
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Treatment Modality
Primary
4,821
Curative
803
Palliative
644
Preventing
555
Diagnostic
324
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CNS Activity
CNS Active
1,896
CNS Penetrant
1,020
CNS Non-penetrant
429
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Originator
Pfizer
217
GlaxoSmithKline
119
Merck
116
Eli Lilly
110
Novartis
99
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Substance Class
Chemical
92,801
Structurally Diverse
26,880
Protein
6,376
Mixture
2,629
Polymer
2,375
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INN Stem
Chemical substance(-ine)
308
Monoclonal antibodies(-mab)
198
Tyrosine-kinase inhibitors(-tinib)
71
Peptides and glycopeptides(-tide)
70
Gene Therapy vectors(-vec)
66
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GInAS Tag
KEW
3,300
84371-57-3
1
ATN-3
1
PUBLIC DOMAIN RELEASE
1
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Code System
FDA UNII
132,111
CAS
96,055
PUBCHEM
91,801
EPA CompTox
66,643
ECHA (EC/EINECS)
28,687
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Protein Type
MONOCLONAL ANTIBODY
878
PEPTIDE
668
ENZYME
483
RECEPTOR
369
MONOCLONAL ANTIBODY CONJUGATE
115
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ATC Level 1
NERVOUS SYSTEM
455
ALIMENTARY TRACT AND METABOLISM
355
CARDIOVASCULAR SYSTEM
336
ANTIINFECTIVES FOR SYSTEMIC USE
334
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
319
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
207
ANTINEOPLASTIC AGENTS
196
OPHTHALMOLOGICALS
162
PSYCHOLEPTICS
156
CARDIAC THERAPY
104
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
129
DIRECT ACTING ANTIVIRALS
71
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
67
ANTITHROMBOTIC AGENTS
65
ANTIPSYCHOTICS
64
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ATC Level 4
Protein kinase inhibitors
44
Antibiotics
43
Other antineoplastic agents
42
Benzodiazepine derivatives
37
Enzymes
36
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Substance Form
Principal Form
132,111
Salts, Hydrates, Esters, etc.
18,037
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Substance Form
Principal Form
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3,4:6,7-Di-O-cyclohexylidene-D-glycero-α-L-talo-heptopyranose
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JFW2F82ZWG
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
3-(Phenylmethyl)-2-pyridinamine
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XJP2636TJY
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
N,N-Bis(2-chloroethyl)-1-butanamine
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FV6ND5JH5Q
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
GOLD MONOBROMIDE
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R3HJY6LTW8
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Methyl (1R,3S)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
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UE3B5MEV9V
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
ISOSTEARAMIDOPROPYL EPOXYPROPYLMORPHOLINIUM CHLORIDE
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JE7Y1B9MGP
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
TRIMETHYLOLPROPANE TRILAURATE
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08S3S2V8PP
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
HYDROXYETHYL CETYLDIMONIUM CHLORIDE
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73JQ08D7IT
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
DIPOTASSIUM AZELATE
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C98170693J
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Other
Class (Stereo):
CHEMICAL (ACHIRAL)
HYDROXYETHYL-P-PHENYLENEDIAMINE SULFATE
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L8W90PN89R
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
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