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Development Status
Other
107,652
Possibly Marketed Outside US
10,255
Investigational
9,777
US Approved Rx
1,612
US Previously Marketed
1,444
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Primary Target
DNA
153
Dopamine D2 receptor
145
Apoptosis
123
GABA-A receptor; anion channel
114
Serotonin 2a (5-HT2a) receptor
112
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Highest Phase
Approved
3,294
Phase II
697
Phase III
386
Phase I
309
Not Provided
289
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Approval Year
Unknown
120,729
2020
647
2012
523
2013
515
1921
496
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Condition
Unknown
1,477
Cancer
395
Pain
281
Hypertension
243
Breast cancer
229
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Treatment Modality
Primary
4,821
Curative
803
Palliative
644
Preventing
555
Diagnostic
324
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CNS Activity
CNS Active
1,896
CNS Penetrant
1,020
CNS Non-penetrant
429
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Originator
Pfizer
217
GlaxoSmithKline
119
Merck
116
Eli Lilly
110
Novartis
99
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Substance Class
Chemical
92,801
Structurally Diverse
26,880
Protein
6,376
Mixture
2,629
Polymer
2,375
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INN Stem
Chemical substance(-ine)
308
Monoclonal antibodies(-mab)
198
Tyrosine-kinase inhibitors(-tinib)
71
Peptides and glycopeptides(-tide)
70
Gene Therapy vectors(-vec)
66
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GInAS Tag
KEW
3,300
84371-57-3
1
ATN-3
1
PUBLIC DOMAIN RELEASE
1
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Code System
FDA UNII
132,111
CAS
96,055
PUBCHEM
91,801
EPA CompTox
66,643
ECHA (EC/EINECS)
28,687
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Protein Type
MONOCLONAL ANTIBODY
878
PEPTIDE
668
ENZYME
483
RECEPTOR
369
MONOCLONAL ANTIBODY CONJUGATE
115
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ATC Level 1
NERVOUS SYSTEM
455
ALIMENTARY TRACT AND METABOLISM
355
CARDIOVASCULAR SYSTEM
336
ANTIINFECTIVES FOR SYSTEMIC USE
334
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
319
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
207
ANTINEOPLASTIC AGENTS
196
OPHTHALMOLOGICALS
162
PSYCHOLEPTICS
156
CARDIAC THERAPY
104
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
129
DIRECT ACTING ANTIVIRALS
71
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
67
ANTITHROMBOTIC AGENTS
65
ANTIPSYCHOTICS
64
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ATC Level 4
Protein kinase inhibitors
44
Antibiotics
43
Other antineoplastic agents
42
Benzodiazepine derivatives
37
Enzymes
36
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Substance Form
Principal Form
132,111
Salts, Hydrates, Esters, etc.
18,037
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Substance Form
Principal Form
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METHYLBUTYLPHENYL HEPTYLBIPHENYLCARBOXYLATE, (2S)-
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5Q8EJN5495
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
N,N-BIS(2-HYDROXYETHYL)-4-TOLUIDINE
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R00STP10PR
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
METHYL P-TERT-BUTYLBENZOATE
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8VK4O27JMT
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
ACETYL PROLINE
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CC8XZ138VZ
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
ACT-777991
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B5B6YF7GWT
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
2-[(3S,4S)-3-[(R)-1-(tert-Butyldimethylsilyloxy)ethyl]-2-oxoazetidin-4-yl]propionic acid, (R)-
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M73QT6DCU4
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Dimethyl 2-sulfoterephthalate
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PZL8HS5EW5
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-amine, (5S,6S,9R)-
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B4ST6XK8MH
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
α-(3-Chloropropyl)-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile, (αS)-
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EXP6QP2S7M
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
YM-466
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9L44969R9Q
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
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