U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 9411 - 9420 of 132111 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Magnesium benzoate is a chemical compound formed from magnesium and benzoic acid. It was once used to treat gout and arthritis. Also, it is used in organic synthesis and as preservative in cosmetics.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


NVP-TNKS656 was identified as an orally active selective tankyrase 2 (TNKS2) inhibitor, which is also antagonist of Wnt pathway activity. On animal models for Colorectal Cancer was shown, that NVP-TNKS656 reduces nuclear β-catenin, reverts such resistance, and represses tumor growth.

Showing 9411 - 9420 of 132111 results