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Class (Stereo):
CHEMICAL (ACHIRAL)
Benoxafos was used as an insecticide agent.
Status:
Investigational
Source:
NCT04478266: Phase 3 Interventional Terminated Breast Cancer
(2020)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
INN:rocbrutinib [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
NCT00758862: Phase 2 Interventional Completed Secondarily Infected Traumatic Lesions (SITL)
(2008)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Class (Stereo):
CHEMICAL (ACHIRAL)
Triampyzine is an anticholinergic, antisecretory agent.
Status:
Investigational
Source:
NCT00362375: Phase 1/Phase 2 Interventional Completed HIV Infections
(2006)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Tenamfetamine (also known as 3,4-methylenedioxyamphetamine (or MDA)) is a hallucinogen that acts as a serotonergic 5-HT2A receptor agonist and releases monoamines by interacting with monoamine plasmalemmal transporters. Tenamfetamine had no accepted medical use and it was scheduled as a controlled substance in the US in 1970. Despite appearing in illicit drug preparations, tenamfetamine has not been studied in humans in over 30 years. In 2010 was published article where was described the action of tenamfetaminea in a clinical trial in humans. In this trial was shown that the drug had induced mystical-type experiences and, in at least some individuals, closed-eye visions. However, during that experiment were impossible to provide strong evidence for changes in the efficacy of top-down influences on perception or acutely increased occipital cortex excitation.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Feclemine is a spasmolytic agent.
Status:
Investigational
Source:
NCT01482221: Phase 2 Interventional Completed Major Depressive Disorder
(2011)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Lanicemine is a low-trapping NMDA channel blocker, which was developed by Fisons Pharmaceuticals and later by AstraZeneca for the treatment of the major depressive disorder. The development was terminated in phase II as the drug did not meet the primary endpoint.
Class (Stereo):
CHEMICAL (ABSOLUTE)
ITROCINONIDE is a synthetic corticosteroid which showed no signs of systemic activity (cortisol depression).
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Isbufylline is a xanthine derivative. This compound exhibits remarkable antibronchospastic properties both in in vitro and in vivo (after oral or intravenous administration) experimental models. Isbufylline is significantly more effective than theophylline in antagonizing bronchospasms elicited by spasmogens (capsaicin, arachidonic acid, PAF and antigen) which mainly act by a local release of biologically active substances proposed to be involved in the pathogenesis of asthma. Isbufylline, unlike theophylline, possesses little or no CNS excitatory properties. Isbufylline exerts a greater inhibitory activity than theophylline on total phosphodiesterase activity in the rat lung.
