U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1681 - 1690 of 132111 results

Status:
Investigational
Source:
INN:embramine [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Embramine or mebrophenhydramine is an antiallergic agent. Embramine is a histamine H₁-receptor antagonist exerting anticholinergic activity. It may inhibit stimulated platelet functions by inhibiting phospholipase A2. It is prescribed for severe allergic conditions.
Status:
Investigational
Source:
INN:alisporivir [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Alisporivir (DEBIO-025) is a first-in-class synthetic cyclophilin inhibitor, in development with Debiopharm as an oral treatment for hepatitis C virus (HCV) infections. Alisporivir has the potential to be used for the treatment of additional diseases such as other viral infections, certain muscular dystrophies, and myocardial infarction. Alisporivir has potent anti-hepatitis C virus (HCV) activity both in vitro and in vivo. It is currently being evaluated in phase II clinical trials.
Status:
Investigational
Source:
INN:rilozarone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Rilozarone has been evaluated as a coronary vasodilator and an antiarrhythmic agent. Rilozarone potentially possesses a variety of cardiovascular effects, which may include Class III effects.
Status:
Investigational
Source:
INN:betoxycaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Betoxycaine was used as a local anesthetic.
Status:
Investigational
Source:
INN:sarsagenin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


PYM50018 (also known as Myogane or SARSAGENIN) has demonstrated neuroprotective effects in several preclinical models. It was observed that PYM50018 protects against neuronal damage, increases neurite outgrowth, reverses oxidative damage and reversed neuronal apoptosis. PYM50018 is in phase I clinical study for the treatment of amyotrophic lateral sclerosis (ALS).
Status:
Investigational
Source:
INN:isomethadone [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

ISOMETHADONE HYDROBROMIDE, DL- is a hydrobromide salt of isomethadone, a synthetic opioid analgesic. This is a controlled substance in the US.
Status:
Investigational
Source:
INN:lanraplenib [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:opevesostat [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT04023240: Phase 2 Interventional Not yet recruiting Cancer
(2023)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:aliflurane
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Aliflurane, a halocarbon drug, is an inhalational anesthetic.

Showing 1681 - 1690 of 132111 results