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Development Status
Other
107,652
Possibly Marketed Outside US
10,255
Investigational
9,777
US Approved Rx
1,612
US Previously Marketed
1,444
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Primary Target
DNA
153
Dopamine D2 receptor
145
Apoptosis
123
GABA-A receptor; anion channel
114
Serotonin 2a (5-HT2a) receptor
112
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Highest Phase
Approved
3,294
Phase II
697
Phase III
386
Phase I
309
Not Provided
289
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Approval Year
Unknown
120,729
2020
647
2012
523
2013
515
1921
496
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Condition
Unknown
1,477
Cancer
395
Pain
281
Hypertension
243
Breast cancer
229
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Treatment Modality
Primary
4,821
Curative
803
Palliative
644
Preventing
555
Diagnostic
324
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CNS Activity
CNS Active
1,896
CNS Penetrant
1,020
CNS Non-penetrant
429
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Originator
Pfizer
217
GlaxoSmithKline
119
Merck
116
Eli Lilly
110
Novartis
99
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Substance Class
Chemical
92,801
Structurally Diverse
26,880
Protein
6,376
Mixture
2,629
Polymer
2,375
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INN Stem
Chemical substance(-ine)
308
Monoclonal antibodies(-mab)
198
Tyrosine-kinase inhibitors(-tinib)
71
Peptides and glycopeptides(-tide)
70
Gene Therapy vectors(-vec)
66
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GInAS Tag
KEW
3,300
84371-57-3
1
ATN-3
1
PUBLIC DOMAIN RELEASE
1
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Code System
FDA UNII
132,111
CAS
96,055
PUBCHEM
91,801
EPA CompTox
66,643
ECHA (EC/EINECS)
28,687
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Protein Type
MONOCLONAL ANTIBODY
878
PEPTIDE
668
ENZYME
483
RECEPTOR
369
MONOCLONAL ANTIBODY CONJUGATE
115
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ATC Level 1
NERVOUS SYSTEM
455
ALIMENTARY TRACT AND METABOLISM
355
CARDIOVASCULAR SYSTEM
336
ANTIINFECTIVES FOR SYSTEMIC USE
334
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
319
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
207
ANTINEOPLASTIC AGENTS
196
OPHTHALMOLOGICALS
162
PSYCHOLEPTICS
156
CARDIAC THERAPY
104
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
129
DIRECT ACTING ANTIVIRALS
71
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
67
ANTITHROMBOTIC AGENTS
65
ANTIPSYCHOTICS
64
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ATC Level 4
Protein kinase inhibitors
44
Antibiotics
43
Other antineoplastic agents
42
Benzodiazepine derivatives
37
Enzymes
36
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Substance Form
Principal Form
132,111
Salts, Hydrates, Esters, etc.
18,037
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Substance Form
Principal Form
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HUMAN IMMUNOGLOBULIN A
MORE DETAILS
741C1PWQ88
Status:
Possibly Marketed Outside US
First approved in 2004
Class:
CONCEPT
BORDETELLA PERTUSSIS PERTACTIN ANTIGEN
MORE DETAILS
63GD90PP8X
Status:
Possibly Marketed Outside US
First approved in 2002
Class:
CONCEPT
TRIMETHYLSILYL TREATED DIMETHICONOL/TRIMETHYLSILOXYSILICATE CROSSPOLYMER (45/55 W/W; 100000 PA.S)
MORE DETAILS
5VBE2X0WG0
Status:
Possibly Marketed Outside US
First approved in 2000
Class:
CONCEPT
DIMETHICONOL/TRIMETHYLSILOXYSILICATE CROSSPOLYMER (40/60 W/W; 1000000 PA.S)
MORE DETAILS
83D19O7250
Status:
Possibly Marketed Outside US
First approved in 1998
Class:
CONCEPT
HAEMOPHILUS INFLUENZAE TYPE B CAPSULAR POLYSACCHARIDE MENINGOCOCCAL OUTER MEMBRANE PROTEIN CONJUGATE ANTIGEN
MORE DETAILS
LUY6P8763W
Status:
US Approved Rx (1989)
First approved in 1989
Class:
CONCEPT
POLAWAX POLYSORBATE
MORE DETAILS
Q504PL8E0V
Status:
Possibly Marketed Outside US
First approved in 1984
Class:
CONCEPT
TRIMETHYLSILYL TREATED DIMETHICONOL/TRIMETHYLSILOXYSILICATE CROSSPOLYMER (40/60 W/W; 5000000 PA.S)
MORE DETAILS
9N5G1G3D3H
Status:
Possibly Marketed Outside US
First approved in 1968
Class:
CONCEPT
EDRECOLOMAB
MORE DETAILS
0KYI9U9FSJ
Status:
Possibly Marketed Outside US
Class:
CONCEPT
HUMAN PAPILLOMAVIRUS TYPE 18 L1 CAPSID PROTEIN RESIDUES 2-472 ANTIGEN
MORE DETAILS
M7H9CF9G0Z
Status:
Possibly Marketed Outside US
Class:
CONCEPT
HUMAN PAPILLOMAVIRUS TYPE 16 L1 CAPSID PROTEIN RESIDUES 2-471 ANTIGEN
MORE DETAILS
7XB76X2V7T
Status:
Possibly Marketed Outside US
Class:
CONCEPT
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