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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
SAR-020106 is an ATP-competitive, potent, and selective inhibitor of CHK1, a serine/threonine kinase associated with DNA damage-linked S and G(2)-M checkpoint control. SAR-020106 is a potent radio- and chemosensitizer in tumor cell lines and in vivo xenograft models.