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microtubule depolymerization

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Histamine H1 receptor

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Dopamine D2 receptor

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Showing 1 - 4 of 4 results

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CABAZITAXEL

51F690397J

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Status:

US Approved Rx (2010)

First approved in 2010

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

microtubule depolymerization

Conditions:

Hormone-refractory metastatic prostate cancer

Cabazitaxel (JEVTANA®) is an antineoplastic agent belonging to the taxane class and is used to treat people with prostate cancer that has progressed despite treatment with docetaxel. It is prepared by semi-synthesis with a precursor extracted from ye...

w needles (10-deacetylbaccatin III). Cabazitaxel (JEVTANA®) is a microtubule inhibitor. It binds to tubulin and promotes its assembly into microtubules while simultaneously inhibiting disassembly. This leads to the stabilization of microtubules, which results in the inhibition of mitotic and interphase cellular functions. The cell is then unable to progress further into the cell cycle, being stalled at metaphase, thus triggering apoptosis of the cancer cell.

CABAZITAXEL ETHYL ACETATE SOLVATE

2HQG2N4L58

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Status:

US Approved Rx (2010)

First approved in 2010

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

microtubule depolymerization

Conditions:

Hormone-refractory metastatic prostate cancer

Cabazitaxel (JEVTANA®) is an antineoplastic agent belonging to the taxane class and is used to treat people with prostate cancer that has progressed despite treatment with docetaxel. It is prepared by semi-synthesis with a precursor extracted from ye...

w needles (10-deacetylbaccatin III). Cabazitaxel (JEVTANA®) is a microtubule inhibitor. It binds to tubulin and promotes its assembly into microtubules while simultaneously inhibiting disassembly. This leads to the stabilization of microtubules, which results in the inhibition of mitotic and interphase cellular functions. The cell is then unable to progress further into the cell cycle, being stalled at metaphase, thus triggering apoptosis of the cancer cell.

CABAZITAXEL MONOHYDRATE

P8B6SWJ0O9

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Status:

US Approved Rx (2010)

First approved in 2010

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

microtubule depolymerization

Conditions:

Hormone-refractory metastatic prostate cancer

Cabazitaxel (JEVTANA®) is an antineoplastic agent belonging to the taxane class and is used to treat people with prostate cancer that has progressed despite treatment with docetaxel. It is prepared by semi-synthesis with a precursor extracted from ye...

w needles (10-deacetylbaccatin III). Cabazitaxel (JEVTANA®) is a microtubule inhibitor. It binds to tubulin and promotes its assembly into microtubules while simultaneously inhibiting disassembly. This leads to the stabilization of microtubules, which results in the inhibition of mitotic and interphase cellular functions. The cell is then unable to progress further into the cell cycle, being stalled at metaphase, thus triggering apoptosis of the cancer cell.

CABAZITAXEL ACETONE

9JX5MZ1I64

Export Data
Search for Structure

Status:

US Approved Rx (2010)

First approved in 2010

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

microtubule depolymerization

Conditions:

Hormone-refractory metastatic prostate cancer

Cabazitaxel (JEVTANA®) is an antineoplastic agent belonging to the taxane class and is used to treat people with prostate cancer that has progressed despite treatment with docetaxel. It is prepared by semi-synthesis with a precursor extracted from ye...

w needles (10-deacetylbaccatin III). Cabazitaxel (JEVTANA®) is a microtubule inhibitor. It binds to tubulin and promotes its assembly into microtubules while simultaneously inhibiting disassembly. This leads to the stabilization of microtubules, which results in the inhibition of mitotic and interphase cellular functions. The cell is then unable to progress further into the cell cycle, being stalled at metaphase, thus triggering apoptosis of the cancer cell.

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