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Primary Target

histone acetylation

5

Histamine H1 receptor

315

Dopamine D2 receptor

297

DNA

278

Bacterial penicillin-binding protein

233

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Development Status

Possibly Marketed Outside US

3

Other

2

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Highest Phase

Approved

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Approval Year

Unknown

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Condition

Hypertension

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Treatment Modality

Primary

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Originator

Biniecki, S.

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Substance Class

Chemical

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Code System

CAS

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FDA UNII

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PUBCHEM

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EPA CompTox

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ChEMBL

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Salts, Hydrates, Esters, etc.

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Principal Form

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Showing 1 - 5 of 5 results

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2-PHENYLBUTYRIC ACID

S7S079H2C2

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

lipid biosynthetic process

histone acetylation

TODRALAZINE

WEN3K83YKD

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Lysosomal alpha-glucosidase

histone acetylation

Conditions:

Todralazine is a hydralazinophthalazine-derived drug currently used in the treatment of arterial hypertension. As vasodilator, it might be used in combination with isosorbide dinitrate. Side effects and drug toxicity were uncommon in such vasodilator...

therapy.

SODIUM 2-PHENYLBUTYRATE

98JNT1MR93

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

lipid biosynthetic process

histone acetylation

TODRALAZINE HYDROCHLORIDE ANHYDROUS

C59540FEXP

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Lysosomal alpha-glucosidase

histone acetylation

Conditions:

Todralazine is a hydralazinophthalazine-derived drug currently used in the treatment of arterial hypertension. As vasodilator, it might be used in combination with isosorbide dinitrate. Side effects and drug toxicity were uncommon in such vasodilator...

therapy.

TODRALAZINE HYDROCHLORIDE MONOHYDRATE

5998D60YO0

Export Data
Search for Structure

Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Lysosomal alpha-glucosidase

histone acetylation

Conditions:

Todralazine is a hydralazinophthalazine-derived drug currently used in the treatment of arterial hypertension. As vasodilator, it might be used in combination with isosorbide dinitrate. Side effects and drug toxicity were uncommon in such vasodilator...

therapy.

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