Showing 1 - 5 of 5 results
Class (Stereo):
CHEMICAL (ABSOLUTE)
Finasteride is a synthetic 4-azasteroid compound. This drug is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). Two distinct isozymes are ...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
3-Oxo-4-aza-5α-androstane-17β-(N-t-butylcarboxamide) (or dihydrofinasteride) is the reduced product of Finasteride. Finasteride acts as an alternate substrate for steroid 5α-reductase and is initially bound in an extremely stable enzyme-bound NADP-di...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Coprostanone is a metabolite of cholesterol. The conversion of cholesterol into coprostanol by intestinal microorganisms has been reported to occur by means of two different pathways. One pathway involves the intermediate formation of delta4-choleles...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Sphinganine is a naturally occurring, skin-identical sphingoid base, a representative of the class of amino alcohols, or long chain bases (LCBs). Sphinganine is a blocker postlysosomal cholesterol transport by inhibition of low-density lipoprotein-in...