U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Showing 1 - 10 of 10 results

Status:
US Approved Rx (2024)
First approved in 2017

Class (Stereo):
CHEMICAL (ABSOLUTE)



AR-13503 is an active metabolite of Netarsudil
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Sotrastaurin, an orally-active, first-in-class immunomodulator, is under development by Novartis for the treatment of uveal melanoma and diffuse-large B-cell lymphoma. Sotrastaurin is a low molecular mass synthetic compound that potently inhibits the...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ruboxistaurin is an orally bioavailable, selective, potent inhibitor of protein kinase C β developed for treating diabetic retinopathy. In vitro and in vivo non-clinical models have demonstrated that Ruboxistaurin decreases PKC β activity and amelio...
Status:
US Approved Rx (2024)
First approved in 2017

Class (Stereo):
CHEMICAL (ABSOLUTE)



AR-13503 is an active metabolite of Netarsudil
Status:
US Approved Rx (2024)
First approved in 2017

Class (Stereo):
CHEMICAL (ABSOLUTE)



AR-13503 is an active metabolite of Netarsudil
Status:
US Approved Rx (2024)
First approved in 2017

Class (Stereo):
CHEMICAL (ABSOLUTE)



AR-13503 is an active metabolite of Netarsudil
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ruboxistaurin is an orally bioavailable, selective, potent inhibitor of protein kinase C β developed for treating diabetic retinopathy. In vitro and in vivo non-clinical models have demonstrated that Ruboxistaurin decreases PKC β activity and amelio...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Sotrastaurin, an orally-active, first-in-class immunomodulator, is under development by Novartis for the treatment of uveal melanoma and diffuse-large B-cell lymphoma. Sotrastaurin is a low molecular mass synthetic compound that potently inhibits the...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ruboxistaurin is an orally bioavailable, selective, potent inhibitor of protein kinase C β developed for treating diabetic retinopathy. In vitro and in vivo non-clinical models have demonstrated that Ruboxistaurin decreases PKC β activity and amelio...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ruboxistaurin is an orally bioavailable, selective, potent inhibitor of protein kinase C β developed for treating diabetic retinopathy. In vitro and in vivo non-clinical models have demonstrated that Ruboxistaurin decreases PKC β activity and amelio...