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Primary Target

Mouse α2βεδ AChRs

3

Histamine H1 receptor

316

Dopamine D2 receptor

311

DNA

282

Serotonin 2a (5-HT2a) receptor

237

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US Approved OTC

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Approval Year

1971

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Condition

Large roundworms infection

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Pinworm infection

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Strongyloidiasis

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Tapeworm infection

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Curative

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Pfizer

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CFR

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ChEMBL

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DAILYMED

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DRUG BANK

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ATC Level 1

ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS

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ANTHELMINTICS

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ANTINEMATODAL AGENTS

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ATC Level 4

Tetrahydropyrimidine derivatives

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PYRANTEL

4QIH0N49E7

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Status:

US Approved OTC

First approved in 1971

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Nicotinic receptors (AChRs) of nematodes

Mouse α2βεδ AChRs

Conditions:

Strongyloidiasis

Pinworm infection

Large roundworms infection

Tapeworm infection

Pyrantel is an anthelmintic, which acts as an agonist of nicotinic receptors (AChRs) of nematodes and exerts its therapeutic effects by depolarizing their muscle membranes. It is used to treat a number of parasitic worm infections. This includes asca...

riasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis and trichinellosis. Common adverse reactions include diarrhea, nausea, vomiting, dizziness, headache and somnolence.

PYRANTEL PAMOATE

81BK194Z5M

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Search for Structure

Status:

US Approved OTC

First approved in 1971

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Nicotinic receptors (AChRs) of nematodes

Mouse α2βεδ AChRs

Conditions:

Strongyloidiasis

Pinworm infection

Large roundworms infection

Tapeworm infection

Pyrantel is an anthelmintic, which acts as an agonist of nicotinic receptors (AChRs) of nematodes and exerts its therapeutic effects by depolarizing their muscle membranes. It is used to treat a number of parasitic worm infections. This includes asca...

riasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis and trichinellosis. Common adverse reactions include diarrhea, nausea, vomiting, dizziness, headache and somnolence.

PYRANTEL TARTRATE

SC82VF0480

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Status:

US Approved OTC

First approved in 1971

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Nicotinic receptors (AChRs) of nematodes

Mouse α2βεδ AChRs

Conditions:

Strongyloidiasis

Pinworm infection

Large roundworms infection

Tapeworm infection

Pyrantel is an anthelmintic, which acts as an agonist of nicotinic receptors (AChRs) of nematodes and exerts its therapeutic effects by depolarizing their muscle membranes. It is used to treat a number of parasitic worm infections. This includes asca...

riasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis and trichinellosis. Common adverse reactions include diarrhea, nausea, vomiting, dizziness, headache and somnolence.

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