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Microtubule-associated protein 2

5

Histamine H1 receptor

315

Dopamine D2 receptor

297

DNA

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Bacterial penicillin-binding protein

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1981

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Carcinoma of the prostate

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Palliative

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Bastian Werk, W. Germany

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ESTRAMUSTINE

35LT29625A

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Status:

US Approved Rx (1981)

First approved in 1981

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

endothelial cell proliferation

Estrogen receptor beta

Estrogen receptor alpha

Microtubule-associated protein 1A

Microtubule-associated protein 2

Conditions:

Carcinoma of the prostate

Estramustine is an antineoplastic agent indicated in the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate. Estramustine is a combination of estradiol with nitrogen mustard. In vivo, the nitrogen-mustard mo...

iety becomes active and participates in alkylation of DNA or other cellular components. This causes DNA damage in rapidly dividing cancerous cells leading to cell death and ideally, tumor shrinkage. Also, due to the drugs estrogen component, it can bind more selectively to active estrogen receptors. Used for the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate.

ESTRAMUSTINE PHOSPHATE MEGLUMINE

C89YOK4N2S

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Status:

US Approved Rx (1981)

First approved in 1981

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

endothelial cell proliferation

Estrogen receptor beta

Estrogen receptor alpha

Microtubule-associated protein 1A

Microtubule-associated protein 2

Conditions:

Carcinoma of the prostate

Estramustine is an antineoplastic agent indicated in the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate. Estramustine is a combination of estradiol with nitrogen mustard. In vivo, the nitrogen-mustard mo...

iety becomes active and participates in alkylation of DNA or other cellular components. This causes DNA damage in rapidly dividing cancerous cells leading to cell death and ideally, tumor shrinkage. Also, due to the drugs estrogen component, it can bind more selectively to active estrogen receptors. Used for the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate.

ESTRAMUSTINE PHOSPHATE SODIUM

75F375MT2N

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Status:

US Approved Rx (1981)

First approved in 1981

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

endothelial cell proliferation

Estrogen receptor beta

Estrogen receptor alpha

Microtubule-associated protein 1A

Microtubule-associated protein 2

Conditions:

Carcinoma of the prostate

Estramustine is an antineoplastic agent indicated in the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate. Estramustine is a combination of estradiol with nitrogen mustard. In vivo, the nitrogen-mustard mo...

iety becomes active and participates in alkylation of DNA or other cellular components. This causes DNA damage in rapidly dividing cancerous cells leading to cell death and ideally, tumor shrinkage. Also, due to the drugs estrogen component, it can bind more selectively to active estrogen receptors. Used for the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate.

ESTRAMUSTINE PHOSPHATE SODIUM ANHYDROUS

IQ856M1R16

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Status:

US Approved Rx (1981)

First approved in 1981

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

endothelial cell proliferation

Estrogen receptor beta

Estrogen receptor alpha

Microtubule-associated protein 1A

Microtubule-associated protein 2

Conditions:

Carcinoma of the prostate

Estramustine is an antineoplastic agent indicated in the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate. Estramustine is a combination of estradiol with nitrogen mustard. In vivo, the nitrogen-mustard mo...

iety becomes active and participates in alkylation of DNA or other cellular components. This causes DNA damage in rapidly dividing cancerous cells leading to cell death and ideally, tumor shrinkage. Also, due to the drugs estrogen component, it can bind more selectively to active estrogen receptors. Used for the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate.

ESTRAMUSTINE PHOSPHATE

MUZ9585Y7B

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Search for Structure

Status:

US Approved Rx (1981)

First approved in 1981

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

endothelial cell proliferation

Estrogen receptor beta

Estrogen receptor alpha

Microtubule-associated protein 1A

Microtubule-associated protein 2

Conditions:

Carcinoma of the prostate

Estramustine is an antineoplastic agent indicated in the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate. Estramustine is a combination of estradiol with nitrogen mustard. In vivo, the nitrogen-mustard mo...

iety becomes active and participates in alkylation of DNA or other cellular components. This causes DNA damage in rapidly dividing cancerous cells leading to cell death and ideally, tumor shrinkage. Also, due to the drugs estrogen component, it can bind more selectively to active estrogen receptors. Used for the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate.

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